Lymphocyte transformation in malnourished children.
نویسندگان
چکیده
Selimeyer, E., Bhettay, E., Truswell, A. S., Meyers, 0. L., and Hansen, J. D. L. (1972). Archives of Disease in Childhood, 47, 429. Lymphocyte transformation in malnourished children. In vitro lymphocyte stimulation with phytohaemagglutinin gave subnormal transformation values in children with proteincalorie malnutrition. It is suggested that impaired cell-mediated immunity may be one important mechanism for the susceptibility of malnourished children to infections. Lymphocyte transformation was also subnormal in children with measles and gastroenteritis but tended to be increased in pneumonia.
منابع مشابه
Lymphocyte subpopulations and antibody levels in immunized malnourished children.
1. The proportions of lymphocyte subpopulations (by rosette tests) and the serum antibody levels (using haemagglutination techniques) were estimated in malnourished and well fed Nigerian children before and up to 21 d after immunization with tetanus toxoid or measles virus vaccine. 2. Significantly diminished (P less than 0.01) mean percentage T lymphocyte levels and considerably higher mean pe...
متن کاملFlow cytometry study of lymphocyte subsets in malnourished and well-nourished children with bacterial infections.
Protein-energy malnutrition is the primary cause of immune deficiency in children across the world. It has been related to changes in peripheral T-lymphocyte subsets. The aim of the present study was to evaluate the effects of infection and malnutrition on the proportion of peripheral-lymphocyte subsets in well-nourished non-bacterium-infected (WN), well-nourished bacterium-infected (WNI), and ...
متن کاملIn vitro lymphocyte-differentiating effects of thymulin (Zn-FTS) on lymphocyte subpopulations of severely malnourished children.
This work investigates how thymic dysfunction contributes to the depression of cell-mediated immunity in protein-energy malnutrition (PEM). In Bolivian children hospitalized for severe PEM, the size of the thymus was measured by echography, and the lymphocyte subpopulations were detected by using monoclonal antibodies. These data were compared with those obtained from healthy control subjects. ...
متن کاملValidity of Antibodies in Lymphocyte Supernatant in Diagnosing Tuberculosis in Severely Malnourished Children Presenting with Pneumonia
BACKGROUND The diagnosis of tuberculosis (TB) in young children can be challenging, especially in severely malnourished children. There is a critical need for improved diagnostics for children. Thus, we sought to evaluate the performance of a technique that measures antibodies in lymphocyte supernatant (ALS) for the diagnosis of TB in severely malnourished children presenting with suspected pne...
متن کاملCorrelation between serum alkaline phosphatase and vitamin D3 levels among 1-14 years old malnourished children- A descriptive observational study
Background: Vitamin D deficiencies are highly prevalent globally, but the correlation between serum alkaline phosphatase and vitamin D3 deficiency among Indian children is seldom investigated. To describe the correlation of vitamin D3 levels and serum alkaline phosphatase levels among children admitted with malnutrition to the pediatric wards of a tertiary care center. Methods: This descriptiv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 47 253 شماره
صفحات -
تاریخ انتشار 1972